| Product Name | CKR-8 Antibody (H-50) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 151-200 mapping within an internal region of CKR-8 of human origin |
| Modification Notes | C-C or b chemokine family members are characterized by a pair of adjacent cysteine residues and serve as potent chemoattractants and activators of monocytes and T cells. C-C chemokine receptor family members include CKR-1, CKR-2A, CKR-2B, CKR-3, CKR-4, CKR-5, CKR-6, CKR-7, CKR-7, CKR-8, CKR-9, CKR-10 and the Duffy blood group antigen.. Each of these receptors are G protein coupled, seven pass transmembrane domain proteins, whose major physiological role is to function in the chemotaxis of T cells and phagocytic cells to areas of inflammation. CKR-8 is expressed on monocytes and type 2 T lymphocytes that are found in lymphoid tissues, such as thymus, spleen and lymph nodes. CKR-8 is a receptor for I-309 and the monocyte inflammatory protein-1 (vMIP-I) and is thought to mediate the activation, migration and proliferation of lymphoid cells. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of CKR-8 of human and, to a lesser extent, mouse and rat origin by WB, IP, IF and ELISA: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 151-200 mapping within an internal region of CKR-8 of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 151-200 mapping within an internal region of CKR-8 of human origin |
| Entrez Gene | 1237 |
|---|
| Application Notes | recommended for detection of CKR-8 of human and, to a lesser extent, mouse and rat origin by WB, IP, IF and ELISA: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
