Application
Western blot analysis of LEPREL4 expression in non-transfected: (A) and human LEPREL4 transfected: (B) 293 whole cell lysates.| Product Name | LEPREL4 Antibody (D-13) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope mapping within an internal region of LEPREL4 of human origin |
| Modification Notes | The synaptonemal complex (SC) is a meiosis-specific nuclear organelle that is involved in chromosomal rearrangements, such as chromosome pairing and recombination, during meiotic prophase. Specifically, the SC forms between two chromosomes during meiosis and serves as a structural bridge that unites homologous chromosomes and mediates chromosomal synapsis and crossing-over. NOL55 (Nucleolar autoantigen No55), also known as SC65 (synaptonemal complex protein SC65) or nucleolar protein No55, is a 437 amino acid protein that localizes to the particulate compartment of the nucleolus during interphase and to the granular compartment and the surface of chromosomes during mitosis. Expressed in normal ovary, prostate and pancreatic tissues and in human prostate cancer cell lines, NOL55 is thought to play an important role in proper cell cycle progression and may serve as a potential antigen for the detection of prostate cancer. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of LEPREL4 of human origin and Sc65 of mouse origin by WB, IP, IF and ELISA non cross-reactive with other NOL family members: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope mapping within an internal region of LEPREL4 of human origin |
|---|---|
| Tissue Specificity | epitope mapping within an internal region of LEPREL4 of human origin |
| Entrez Gene | 10609 |
|---|
Application
Western blot analysis of LEPREL4 expression in non-transfected: (A) and human LEPREL4 transfected: (B) 293 whole cell lysates.| Application Notes | recommended for detection of LEPREL4 of human origin and Sc65 of mouse origin by WB, IP, IF and ELISA non cross-reactive with other NOL family members: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
