Application
Western blot analysis of PLEKHN1 expression in non-transfected: (A) and human PLEKHN1 transfected: (B) 293T whole cell lysates.| Product Name | PLEKHN1 Antibody (T-13) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope mapping within an internal region of PLEKHN1 of human origin |
| Modification Notes | PLEKHN1 (pleckstrin homology domain containing, family N member 1) is a 663 amino acid phosphoprotein that contains two pleckstrin homology (PH) domains. Conserved in dog, cow, mouse and rat, PLEKHN1 exists as three alternatively spliced isoforms and is encoded by a gene that maps to human chromosome 1p36.33. As the largest human chromosome, chromosome 1 makes up approximately 8% of the human genome and contains 260 million base pairs encoding 3,000 genes. Numerous diseases are linked to chromosome 1, such as the rare aging disease Hutchinson-Gilford progeria, familial adenomatous polyposis, Stickler syndrome, Parkinson’s disease, Gaucher disease and Usher syndrome. Aberrations in chromosome 1 also exist in a variety of cancers, including head and neck cancer, malignant melanoma and multiple myeloma. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of PLEKHN1 isoforms 1-3 of human origin by WB, IP, IF and ELISA also reactive with additional species, including canine: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope mapping within an internal region of PLEKHN1 of human origin |
|---|---|
| Tissue Specificity | epitope mapping within an internal region of PLEKHN1 of human origin |
| Entrez Gene | 84069 |
|---|
Application
Western blot analysis of PLEKHN1 expression in non-transfected: (A) and human PLEKHN1 transfected: (B) 293T whole cell lysates.| Application Notes | recommended for detection of PLEKHN1 isoforms 1-3 of human origin by WB, IP, IF and ELISA also reactive with additional species, including canine: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
