| Product Name | TMED2 Antibody (H-108) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 94-201 mapping at the C-terminus of TMED2 of human origin |
| Modification Notes | TMED2 (transmembrane emp24 domain trafficking protein 2), also known as P24A or RNP24, is a 201 amino acid protein that is a member of the EMP24/GP25L family. Like most members of this family, TMED2 is a single-pass type I membrane protein containing one GOLD domain. The GOLD (golgi dynamics) domain is a region of about 90 to 150 amino acids that mediates protein-protein interactions. The GOLD domain interacts with lipid, sterol or fatty acid-domains as well as with RUN domains, which interact with cytoskeletal filaments of membrane proteins. TMED2 is thought to inhibit GTPase-activating activity of ARFGAP1 and may have a role in the budding of coatomer-coated and other species of coated vesicles. As part of a complex composed of SURF-4 and TMP21, TMED2 binds to cargo molecules to collect them into budding vesicles. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of TMED2 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine, porcine and avian: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 94-201 mapping at the C-terminus of TMED2 of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 94-201 mapping at the C-terminus of TMED2 of human origin |
| Entrez Gene | 10959 |
|---|
| Application Notes | recommended for detection of TMED2 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine, porcine and avian: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
