Application
Western blot analysis of Rho T2 expression in mouse testis tissue extract.| Product Name | Rho T2 Antibody (H-45) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 71-115 mapping near the N-terminus of Rho T2 of human origin |
| Modification Notes | The Rho subfamily of Ras-related GTPases controls multiple aspects of cell function, including cytoskeletal rearrangement, nuclear signaling and cell growth. Rho T2 (Ras homolog gene family, member T2), also known as ARHT2, RASL or MIRO-2 (mitochondrial Rho GTPase 2), is a 618 amino acid single-pass type IV membrane protein that functions as a GTPase during mitochondrial trafficking. Existing as two alternatively spliced isoforms, Rho T2 is ubiquitously expressed with highest levels found in pancreas, heart, kidney and skeletal muscle. Rho T2 is thought to influence anterograde transport of mitochondria and associates with kinesin-binding proteins, such as OIP106 and GRIF-1, to link mitochondria to microtubules. Rho T2 contains two EF-hand domains and two miro domains, and is encoded by a gene that maps to human chromosome 16p13.3. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of Rho T2 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine and porcine: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 71-115 mapping near the N-terminus of Rho T2 of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 71-115 mapping near the N-terminus of Rho T2 of human origin |
| Entrez Gene | 89941 |
|---|
Application
Western blot analysis of Rho T2 expression in mouse testis tissue extract.| Application Notes | recommended for detection of Rho T2 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine and porcine: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
