epitope mapping within an internal region of TMEM183B of human origin
Modification Notes
TMEM183 (transmembrane protein 183), also known as Tmem183a or MNCb-2755, is a 375 amino acid membrane protein that belongs to the TMEM183 family. The gene that encodes TMEM183 maps to murine chromosome 1. Mouse chromosome 1 houses over 1,500 genes, some of which encode proteins such as nuclear receptor coactivators, coatomer complex subunits, synaptotagmins and olfactory receptors. In mice, chromosome 1 is the site of several recombination hotspots, indicating that chromosome 1 may play an important role in genetic diversity. Defects in chromosome 1-localized genes are associated with a variety of conditions, including autoimmune myocarditis, lymphocyte cell death, catalepsy, infantile neuroaxonal dystrophy and lung carcinomas.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WBIPIFELISA
recommended for detection of TMEM183A and TMEM183B of human origin and TMEM183 of mouse and rat origin by WB, IP, IF and ELISA non cross-reactive with other TMEM family members also reactive with additional species, including equine, canine, bovine and porcine:
Species Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Alternative Names
epitope mapping within an internal region of TMEM183B of human origin
Tissue Specificity
epitope mapping within an internal region of TMEM183B of human origin
Western blot analysis of TMEM183 expression in non-transfected: (A) and mouse TMEM183 transfected: (B) 293T whole cell lysates.
Application Notes
recommended for detection of TMEM183A and TMEM183B of human origin and TMEM183 of mouse and rat origin by WB, IP, IF and ELISA non cross-reactive with other TMEM family members also reactive with additional species, including equine, canine, bovine and porcine:
Additional Information
Form
Liquid
Storage Instructions
For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.