Application
Western blot analysis of human recombinant Neuro D fusion protein.| Product Name | Neuro D Antibody (H-76) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 281-356 mapping at the C-terminus of Neuro D of human origin |
| Modification Notes | The basic helix-loop-helix (bHLH) proteins are transcription factors that are required for several aspects of development, including cell type determination, terminal differentiation and sex determination. The HLH domain is required for dimerization, while the basic region makes specific contacts with DNA. Members of the myogenic determination family, MyoD, myf5, myogenin and MRF4, all have bHLH domains. These proteins heterodimerize with members of the E protein family and initiate myogenesis. Neuro D has been identified as a bHLH transcription factor functioning in neurogenic differentiation. Neuro D is expressed transiently in a subset of neurons in the central and peripheral nervous systems at the time of their terminal differentiation into mature neurons. Moreover, ectopic expression of Neuro D in Xenopus embryos induces premature differentiation of neuronal precursors and Neuro D can convert presumptive epidermal cells into neurons. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of Neuro D of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including canine, bovine and porcine: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 281-356 mapping at the C-terminus of Neuro D of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 281-356 mapping at the C-terminus of Neuro D of human origin |
| Entrez Gene | 4760 |
|---|
Application
Western blot analysis of human recombinant Neuro D fusion protein.| Application Notes | recommended for detection of Neuro D of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including canine, bovine and porcine: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
