| Product Name | PLC-L Antibody (H-65) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 121-185 of PLC lung form of human origin |
| Modification Notes | Phosphoinositide-specific phospholipase C (PLC) plays a critical role in the initiation of receptor mediated signal transduction through the generation of the two second messengers, inositol 1, 4, 5-triphosphate and diacylglycerol from phosphatidylinositol 4, 5 bisphosphate. A total of nine mammalian PLC isozymes have been described. PLC-L (for PLC-deleted in lung carcinoma) is a PLC family memeber, the expression of which is decreased in small cell lung carcinomas. PLC-L is normally expressed in a variety of fetal and adult organs including the lung. PLC-L is thought to be involved in inositol phospholipid-based intracellular signaling cascade and aberrant expression of PLC-L may contributes to the genesis or progression of human lung carcinoma. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of PLC lung form of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine, porcine and avian: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 121-185 of PLC lung form of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 121-185 of PLC lung form of human origin |
| Entrez Gene | 5334 |
|---|
| Application Notes | recommended for detection of PLC lung form of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine, porcine and avian: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
