epitope mapping within an internal region of CTNNBL1 of human origin
Modification Notes
CTNNBL1 (catenin, ∫ like 1), also known as NAP (nuclear-associated protein) or P14L, is an evolutionarily conserved protein with structural homology to members of the armadillo family, including ∫-catenin. CTNNBL1 is expressed in a variety of tissues with highest expression levels found in heart, spleen, testis, placenta, thyroid and skeletal muscle. Localizing to the nucleus, CTNNBL1 contains a bipartite nuclear localization signal, an acidic domain, a leucine-isoleucine zipper, an acidic domain and phosphorylation sites. Via its C-terminus, CTNNBL1 is believed to play a role in apoptosis. In addition, multiple SNPs (single nucleotide polymorphisms) in the CTNNBL1 have been associated with fat mass and body mass index (BMI), suggesting a possible role for CTNNBL1 in the development of obesity.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WBIPIFELISA
recommended for detection of CTNNBL1 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine and porcine:
Species Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Alternative Names
epitope mapping within an internal region of CTNNBL1 of human origin
Tissue Specificity
epitope mapping within an internal region of CTNNBL1 of human origin
Western blot analysis of CTNNBL1 expression in K-562 nuclear extract.
Application Notes
recommended for detection of CTNNBL1 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine and porcine:
Additional Information
Form
Liquid
Storage Instructions
For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.