epitope corresponding to amino acids 1-172 representing full length podoplanin of mouse origin
Modification Notes
Puromycin aminonucleoside nephrosis (PAN) is a rat model for human minimal change nephropathy. During PAN, severe proteinuria is induced that is paralleled by a reduced expression of a rat podocyte protein, named podoplanin. Podoplanin, also known as glycoprotein 38 (gp38) is a type I membrane protein. Podoplanin localizes in stromal cells of peripheral lymphoid tissue and thymic epithelial cells. As a regulator of the lymphatic endothelium, podoplanin probably plays a role in maintaining the unique shape of podocytes.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WBIPIFELISA
recommended for detection of podoplanin of mouse and rat origin by WB, IP, IF and ELISA:
Species Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Alternative Names
epitope corresponding to amino acids 1-172 representing full length podoplanin of mouse origin
Tissue Specificity
epitope corresponding to amino acids 1-172 representing full length podoplanin of mouse origin
Application
Application
Western blot analysis of podoplanin expression in mouse kidney (A) and mouse lymph node (B) tissue extracts.
Application Notes
recommended for detection of podoplanin of mouse and rat origin by WB, IP, IF and ELISA:
Additional Information
Form
Liquid
Storage Instructions
For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.