epitope corresponding to amino acids 111-240 mapping within an internal region of MATP of human origin
Modification Notes
The membrane-associated transporter protein (MATP) is a 530 amino acid protein that spans the lipid bilayer 12 times. MATP is a melanocyte differentiation antigen that is expressed in a high percentage of melanoma cell lines. MATP is transcriptionally modulated by MITF, a melanocyte-specific transcription factor that may act indirectly or bind to a remote regulatory sequence. MATP may play a role in skin cancer, as its gene is expressed in a high percentage of melanoma cell lines, but not at significant levels in normal tissues. Mutations in the MATP gene have also been linked to albinism.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WBIPIFELISA
recommended for detection of MATP of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including porcine:
Species Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Alternative Names
epitope corresponding to amino acids 111-240 mapping within an internal region of MATP of human origin
Tissue Specificity
epitope corresponding to amino acids 111-240 mapping within an internal region of MATP of human origin