Application
Western blot analysis of USMG5 expression in human heart tissue extract.| Product Name | USMG5 Antibody (A-14) |
|---|---|
| Antibody Type | Primary Antibodies |
| Modification Notes | USMG5 (up-regulated during skeletal muscle growth 5 homolog), also known as HCV F-transactivated protein 2 (HCVFTP2), is a 58 amino acid protein single-pass membrane protein that is transactivated by SBP1. The gene encoding USMG5 maps to human chromosome 10, which contains over 800 genes and 135 million nucleotides, making up nearly 4.5% of the human genome. PTEN is an important tumor suppressor gene located on chromosome 10 and, when defective, causes a genetic predisposition to cancer development known as Cowden syndrome. The chromosome 10 encoded gene ERCC6 is important for DNA repair and is linked to Cockayne syndrome which is characterized by extreme photosensitivity and premature aging. Tetrahydrobiopterin deficiency and a number of syndromes involving defective skull and facial bone fusion are also linked to chromosome 10. As with most trisomies, trisomy 10 is rare and is deleterious. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of USMG5 of human and rat origin by WB, IP, IF and ELISA also reactive with additional species, including equine and porcine | |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope mapping at the N-terminus of USMG5 of human origin |
|---|---|
| Tissue Specificity | epitope mapping at the N-terminus of USMG5 of human origin |
| Entrez Gene | 84833 |
|---|
Application
Western blot analysis of USMG5 expression in human heart tissue extract.| Application Notes | recommended for detection of USMG5 of human and rat origin by WB, IP, IF and ELISA also reactive with additional species, including equine and porcine |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
