| Product Name | p8 Antibody (FL-82) |
|---|---|
| Antibody Type | Primary Antibodies |
| Modification Notes | The human p8 (candidate of metastasis 1) gene maps to chromosome 16p11.2 and encodes a transcription factor that regulates pancreatic growth. p8 upregulates the glucagon gene promoter by recruiting the p300 cofactor to increase Pax2A and Pax2B activity and by binding the Pax2-interacting protein PTIP to suppress its inhibition. p8 is present at high levels in pancreatic acinar cells during the acute phase of pancreatitis in developing pancreas and during pancreatic regeneration. Acinar cells upregulate p8 mRNA in response to cellular pancreatitis-induced injury. In vitro studies suggest that p8 mRNA is induced in pancreatic and non-pancreatic cells in response to apoptotic stimuli. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of p8 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including canine | |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 1-82 representing full length p8 of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 1-82 representing full length p8 of human origin |
| Entrez Gene | 26471 |
|---|
| Application Notes | recommended for detection of p8 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including canine |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
