| Product Name | Mcm2 Antibody (y-100) |
|---|---|
| Antibody Type | Primary Antibodies |
| Modification Notes | Orc1 and Orc2 (also designated Rrr1 or Sir5) are two of the six subunits that compose the yeast origin of replication complex (ORC). This complex binds to autonomously replicating sequences (ARS) and serves as an initiator protein for DNA replication (1). The minichromosome maintenance (MCM) proteins also play an essential role in regulating DNA replication by binding to chromatin and activating the ORC-ARS complex (2-6). Cdc6, involved in limiting DNA replication to once per cell cycle, binds to the ORC and is essential for the assembly of the MCM proteins (7). The transcription factor Abf1 (also designated Obf1 or Baf1) also binds to the ARS, and plays a role in gene silencing as well as in DNA replication (8). |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of Mcm2 of Saccharomyces cerevisiae origin by WB, IP, IF and ELISA | |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 1-100 mapping at the N-terminus of Mcm2 of Saccharomyces cerevisiae origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 1-100 mapping at the N-terminus of Mcm2 of Saccharomyces cerevisiae origin |
| Application Notes | recommended for detection of Mcm2 of Saccharomyces cerevisiae origin by WB, IP, IF and ELISA |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
