Application
Western blot analysis of β-defensin 4 expression in mouse lung tissue extract.| Product Name | β-defensin 4 Antibody (M-43) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 21-63 of β-defensin 4 of mouse origin |
| Modification Notes | ∫-defensins (also designated BD, and hBD in human) are small cationic peptides with broad-spectrum antimicrobial activity. Produced in mucosal epithelia and neutrophils of several species, ∫-defensins are developmentally regulated. Unlike the other previously described human ∫-defensins, human ∫-defensin 4 (hBD-4) expression is restricted to a few tissues, with highest expression in testis. A restricted pattern is also exhibited by mouse ∫-defensin 4. Rat ∫-defensin 4 (also desiganated BD-4, RBD-4, BD-2, and RBD-2) is developmentally regulated in the lung and is predominantly expressed in the lung and, to a lesser extent, in the trachea and tongue. It exhibits a regulation pattern similar to that of specific genes involved in host defense around the time of birth. The selectivity in both expression pattern and antimicrobial activity of human ∫-defensin 4 suggests that it is best suited to act at the epithelial locations where it is expressed. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of β-defensin 4 of mouse origin by WB, IP, IF and ELISA: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 21-63 of &beta -defensin 4 of mouse origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 21-63 of β-defensin 4 of mouse origin |
| Entrez Gene | 56519 |
|---|
Application
Western blot analysis of β-defensin 4 expression in mouse lung tissue extract.| Application Notes | recommended for detection of β-defensin 4 of mouse origin by WB, IP, IF and ELISA: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
