| Product Name | CHD7 Antibody (H-300) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 297-596 mapping within an internal region of CHD7 of human origin |
| Modification Notes | Chromodomain-helicase-DNA-binding protein 7 (CHD7) is a 2997 amino acid member of the SNF2/RAD54 helicase family of proteins and contains two chromo domains, one helicase ATP-binding domain and one helicase C-terminal domain. Highly expressed in both fetal and adult brain, CHD7 is thought to be a potential transcription regulator. Mutations in the gene encoding CHD7 have been shown to cause CHARGE syndrome, a common cause of congenital anomalies, including choanal atresia and malformations of the heart, inner ear and retina. Defects in the CHD7 gene has also been linked to increased susceptibility to idiopathic scoliosis, the most common spinal deformity in children. Two isoforms of CHD7 exist as a result of alternative splicing events. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of CHD7 of mouse and human origin by WB, IP, IF and ELISA: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 297-596 mapping within an internal region of CHD7 of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 297-596 mapping within an internal region of CHD7 of human origin |
| Entrez Gene | 55636 |
|---|
| Application Notes | recommended for detection of CHD7 of mouse and human origin by WB, IP, IF and ELISA: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
