Application
Western blot analysis of β-defensin 1 expression in non-transfected: (A) and mouse β-defensin 1 transfected: (B) 293T whole cell lysates.| Product Name | β-defensin 1 Antibody (M-69) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 1-69 representing full length β-defensin 1 of mouse origin |
| Conjugation | Agarose |
| Modification | Acetylated |
| Modification Notes | ß-defensins (also designated BD, and HBD in human) are small cationic peptides with broad-spectrum antimicrobial activity (1–4). ∫-defensins are involved in the resistance of epithelial surfaces, such as airway surface fluid, to microbial colonization (1–4). Produced in mucosal epithelia and neutrophils of several species, ß-defensins are developmentally regulated (1). Human ß-defensin 1 shares homology with other ∫-defensins from human blood filtrate and is also present in nanomolar concentrations in human plasma (1,5). In addition to the antimicrobial activity of human airway epithelia, ß-defensin 1 may play a role in the mucosal defenses of the lung (1). |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | ELISAIFIPWB |
| WB:1:100~1:500 IP:1:20~1:100 IF:1:20~1:100 |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 1-69 representing full length β-defensin 1 of mouse origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 1-69 representing full length β-defensin 1 of mouse origin |
| Entrez Gene | 13214 |
|---|
Application
Western blot analysis of β-defensin 1 expression in non-transfected: (A) and mouse β-defensin 1 transfected: (B) 293T whole cell lysates.| Application Notes | WB:1:100~1:500 IP:1:20~1:100 IF:1:20~1:100 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
