Application
Western blot analysis of HMG-2L1 expression in c4 whole cell lysate.Application
Western blot analysis of HMG-2L1 expression in non-transfected: (A) and human HMG-2L1 transfected: (B) 293T whole cell lysates.| Product Name | HMG-2L1 Antibody (H-179) |
|---|---|
| Antibody Type | Primary Antibodies |
| Modification Notes | High mobility group (HMG) protein 1 and 2 have been classified by DNA binding preferences and are ubiquitous non-histone components of chromatin. They bind to the minor groove of AT-rich DNA sequences with high affinity. Evidence suggests that the binding of HMG proteins to DNA induces alterations in the DNA architecture including DNA bending and unwinding of the helix. HMG proteins synergize with Oct-2, members of the NFkB family, ATF-2 and c-Jun to activate transcription. HMG-2L1 (High mobility group protein 2-like 1), also known as HMGBCG, is a member of the HMG chromosomal protein superfamily. It contains a single HMG box DNA binding domain, and therefore does not contain an acidic C-terminal tail. HMG-2L1 is expressed in the nucleus and may play a role in transcriptional regulation. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of HMG-2L1 of mouse, rat and human origin by WB, IP, IF and ELISA non cross-reactive with other HMG family members also reactive with additional species, including equine, canine, bovine, porcine and avian | |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 409-587 mapping near the C-terminus of HMG-2L1 of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 409-587 mapping near the C-terminus of HMG-2L1 of human origin |
| Entrez Gene | 10042 |
|---|
Application
Western blot analysis of HMG-2L1 expression in c4 whole cell lysate.
Application
Western blot analysis of HMG-2L1 expression in non-transfected: (A) and human HMG-2L1 transfected: (B) 293T whole cell lysates.| Application Notes | recommended for detection of HMG-2L1 of mouse, rat and human origin by WB, IP, IF and ELISA non cross-reactive with other HMG family members also reactive with additional species, including equine, canine, bovine, porcine and avian |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
