The Adiponutrin family consists of Adiponutrin (ADPN), adipocyte triglyceride lipase (ATGL, also designated Desnutrin), GS1, GS2, GS2-like and PNPLA1. ADPN, ATGL and GS2 display lipase activity, which is dependent upon the presence of an activated serine residue. GS1, also designated DXF68S1E or haloacid dehalogenase-like hydrolase domain containing 1A (HDHD1A), is a 214-amino acid protein that is detected in human placenta and fibroblasts. The gene which encodes for GS1, HDHD1A, is of interest because it is an X-linked gene that escapes X-inactivation. This characteristic of the HDHD1A gene is particularly important in the understanding of human X chromosome structural organization as well as the mechanism of X-inactivation.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WBIPIFELISA
recommended for detection of GS1 of mouse, rat and, to a lesser extent, human origin by WB, IP, IF and ELISA
Species Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Alternative Names
epitope corresponding to amino acids 1-234 representing full length GS1 of mouse origin
Tissue Specificity
epitope corresponding to amino acids 1-234 representing full length GS1 of mouse origin
Application
Application
Western blot analysis of GS1 expression in non-transfected: (A) and human GS1 transfected: (B) 293T whole cell lysates.
Application Notes
recommended for detection of GS1 of mouse, rat and, to a lesser extent, human origin by WB, IP, IF and ELISA
Additional Information
Form
Liquid
Storage Instructions
For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.