| Product Name | IL-17RC Antibody (P-14) |
|---|---|
| Antibody Type | Primary Antibodies |
| Modification Notes | The interleukins (ILs) are a broad family of well characterized cytokines, primarily of hematopoietic cell origin, and are secreted by immune cells (mainly macrophages, B-cells or T-cells) that regulate a wide range of immune system functions. The specific functions of different interleukins vary from the regulation of inflammatory and immune responses to the regulation of other interleukins. They exert their biological effects through the binding of membrane-bound receptors which, in turn, initiate signal transduction cascades and elicit physiological changes in their target cell. IL-17RC (interleukin 17 receptor C) is a 791 amino acid single-pass type I transmembrane protein that may function as a receptor for IL-17. Existing as multiple alternatively spliced isoforms, IL-17RC is expressed in heart, brain, intestine, liver, kidney, lung, muscle, placenta and prostate and is encoded by a gene which maps to human chromosome 3. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIFELISA |
| recommended for detection of IL-17RC of mouse, rat and human origin by WB, IF and ELISA non cross-reactive with other IL family members also reactive with additional species, including equine and porcine | |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope mapping within an extracellular domain of IL-17RC of human origin |
|---|---|
| Tissue Specificity | epitope mapping within an extracellular domain of IL-17RC of human origin |
| Entrez Gene | 84818 |
|---|
| Application Notes | recommended for detection of IL-17RC of mouse, rat and human origin by WB, IF and ELISA non cross-reactive with other IL family members also reactive with additional species, including equine and porcine |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
