Application
Western blot analysis of UHMK1 expression in mouse heart tissue extract.Application
Immunoperoxidase staining of formalin-fixed, paraffin-embedded human hepatocarcinoma tissue showing cytoplasmic localization.| Product Name | UHMK1 Antibody (F-21) |
|---|---|
| Antibody Type | Primary Antibodies |
| Modification Notes | The phosphorylation and dephosphorylation of proteins on serine and threonine residues is an essential means of regulating a broad range of cellular functions in eukaryotes, including cell division, homeostasis and apoptosis. A group of proteins that are intimately involved in this process are the serine/threonine (Ser/Thr) protein kinases. UHMK1 (U2AF homology motif kinase 1), also known as KIS (kinase interacting with stathmin) or KIST, is a 419 amino acid nuclear protein that contains one protein kinase domain and one RRM domain and belongs to the Ser/Thr protein kinase family. Expressed in a variety of tissues with highest levels present in placenta, kidney and skeletal muscle, UHMK1 functions to catalyze the ATP-dependent phosphorylation of target proteins, such as p27, and is thought to be involved in cell cycle regulation, as well as in the trafficking and processing of RNA. Multiple isoforms of UHMK1 exist due to alternative splicing events. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFIHCELISA |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | recommended for detection of UHMK1 of mouse and human origin by WB IP IF IHC(P) ELISA |
|---|---|
| Tissue Specificity | recommended for detection of UHMK1 of mouse and human origin by WB, IP, IF, IHC(P), ELISA |
| Entrez Gene | 127933 |
|---|
Application
Western blot analysis of UHMK1 expression in mouse heart tissue extract.
Application
Immunoperoxidase staining of formalin-fixed, paraffin-embedded human hepatocarcinoma tissue showing cytoplasmic localization.| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
