Application
Immunoperoxidase staining of formalin fixed, paraffin-embedded human stomach showing cytoplasmic and nuclear staining of glandular cells at low magnification. Kindly provided by The Swedish Human Protein Atlas (HPA) program.Application
Immunoperoxidase staining of formalin fixed, paraffin-embedded human stomach showing cytoplasmic and nuclear staining of glandular cells at high magnification. Kindly provided by The Swedish Human Protein Atlas (HPA) program.Application
Western blot analysis of NDUFB4 expression in Ramos whole cell lysate.| Product Name | NDUFB4 Antibody (P-12) |
|---|---|
| Antibody Type | Primary Antibodies |
| Modification Notes | NDUFB4 (NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 4), also known as B15 or CI-B15, is a 129 amino acid single-pass membrane protein. Localized to the matrix side of the inner mitochondrial membrane, NDUFB4 functions as an accessory subunit of the multi-protein mitochondrial membrane respiratory chain NADH dehydrogenase complex (known as Complex I). Complex I plays an important role in the transfer of electrons from NADH to the respiratory chain, a process that is essential for cellular respiration. The gene encoding NDUFB4 maps to human chromosome 3, which houses over 1,100 genes, including a chemokine receptor (CKR) gene cluster and a variety of human cancer-related gene loci. Key tumor suppressing genes on chromosome 3 include those that encode the apoptosis mediator RASSF1, the cell migration regulator HYAL1 and the angiogenesis suppressor SEMA3B. Marfan Syndrome, porphyria, von Hippel-Lindau syndrome, osteogenesis imperfecta and Charcot-Marie-Tooth Disease are a few of the numerous genetic diseases associated with chromosome 3. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFIHCELISA |
| recommended for detection of NDUFB4 of human origin by WB, IP, IF, IHC(P) and ELISA non cross-reactive with other NDUFB family members | |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope mapping within an internal region of NDUFB4 of human origin |
|---|---|
| Tissue Specificity | epitope mapping within an internal region of NDUFB4 of human origin |
| Entrez Gene | 4710 |
|---|
Application
Immunoperoxidase staining of formalin fixed, paraffin-embedded human stomach showing cytoplasmic and nuclear staining of glandular cells at low magnification. Kindly provided by The Swedish Human Protein Atlas (HPA) program.
Application
Immunoperoxidase staining of formalin fixed, paraffin-embedded human stomach showing cytoplasmic and nuclear staining of glandular cells at high magnification. Kindly provided by The Swedish Human Protein Atlas (HPA) program.
Application
Western blot analysis of NDUFB4 expression in Ramos whole cell lysate.| Application Notes | recommended for detection of NDUFB4 of human origin by WB, IP, IF, IHC(P) and ELISA non cross-reactive with other NDUFB family members |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
