| Product Name | PIG-Z Antibody (N-16) |
|---|---|
| Antibody Type | Primary Antibodies |
| Modification Notes | Several cell surface proteins are attached to the membrane through their C-terminal domain and a glycosylphosphatidylinositol (GPI) moiety. Phosphatidylinositol-glycans (PIGs) are multi-pass transmembrane proteins that localize to the endoplasmic reticulum. PIGs are crucial for the synthesis of very early intermediates in GPI-anchor biosynthesis. PIG-Z (Phosphatidylinositol-glycan biosynthesis class Z protein), also known as GPI mannosyltransferase 4 and SMP3, is a 579 amino acid endoplasmic reticular protein that transfers the fourth mannose to some trimannosyl-GPIs during GPI precursor assembly. Since the presence of a fourth mannose in GPI is rarely detected, it is likely that it only exists in certain tissues. PIG-Z is widely expressed at very low levels, with highest expression in colon and brain. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIFELISA |
| recommended for detection of PIG-Z of mouse and human origin by WB, IF and ELISA non cross-reactive with other PIG family members also reactive with additional species, including equine, canine, porcine and avian | |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope mapping near the N-terminus of PIG-Z of human origin |
|---|---|
| Tissue Specificity | epitope mapping near the N-terminus of PIG-Z of human origin |
| Entrez Gene | 80235 |
|---|
| Application Notes | recommended for detection of PIG-Z of mouse and human origin by WB, IF and ELISA non cross-reactive with other PIG family members also reactive with additional species, including equine, canine, porcine and avian |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
