| Product Name | Myosin XVIIIa Antibody (H-125) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 1656-1780 mapping within an internal region of Myosin XVIIIa of human origin |
| Modification Notes | Myosin XVIIIa, also designated MYO18A, MAJN, MYSPDZ, surfactant protein A receptor (SPR210) or TGF∫1-induced antiapoptotic factor 1, is a TGF∫1-induced antiapoptotic factor known to inhibit the cytotoxic effects of TNFå on mouse fibroblasts. Two isoforms of mouse Myosin XVIIIa, designated MysPDZ å and MysPDZ∫, have been identified. MysPDZå consists of a KE-rich region, an N-terminal PDZ domain, and a prevalent myosin homologous head region, neck (with one IQ motif) and coiled-coil tail. The MysPDZ∫ isoform lacks the KE-rich region and PDZ domain. MysPDZå is present in most tissues and is known to co-localize with the ER-Golgi complex and with membrane ruffles and filopodia. MysPDZ∫ is expressed specifically in hematopoietic tissues and cell lines and shows dispersed localization in the cytoplasm. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of Myosin XVIIIa isoforms 1-5 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine and bovine: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 1656-1780 mapping within an internal region of Myosin XVIIIa of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 1656-1780 mapping within an internal region of Myosin XVIIIa of human origin |
| Entrez Gene | 399687 |
|---|
| Application Notes | recommended for detection of Myosin XVIIIa isoforms 1-5 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine and bovine: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
