Application
Western blot analysis of NKX1-1 expression in SP2/0 whole cell lysate.| Product Name | NKX1-1 Antibody (P-21) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | raised against synthetic NKX1-1 peptide of mouse origin |
| Modification Notes | The homeobox DNA-binding domain is a 60 amino acid motif that is conserved among many species and functions to bind DNA via a helix-turn-helix structure, thereby playing a role in transcriptional regulation and the control of gene expression. NKX1-1 (NK1 transcription factor-related protein 1), also known as HPX153 (Homeobox protein 153), is a 411 amino acid nuclear protein that is expressed in progenitor cells and contains one homeobox DNA-binding domain, suggesting a role in transcriptional regulation. The gene encoding NKX1-1 maps to human chromosome 4, which encodes nearly 6% of the human genome and has the largest gene deserts (regions of the genome with no protein encoding genes) of all of the human chromosomes. Defects in some of the genes located on chromosome 4 are associated with Huntington's disease, Ellis-van Creveld syndrome, methylmalonic acidemia and polycystic kidney disease. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPELISA |
| recommended for detection of NKX1-1 of mouse, rat and human origin by Western Blotting and ELISA: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | raised against synthetic NKX1-1 peptide of mouse origin |
|---|---|
| Tissue Specificity | raised against synthetic NKX1-1 peptide of mouse origin |
| Entrez Gene | 54729 |
|---|
Application
Western blot analysis of NKX1-1 expression in SP2/0 whole cell lysate.| Application Notes | recommended for detection of NKX1-1 of mouse, rat and human origin by Western Blotting and ELISA: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
