Application
Western blot analysis of T3JAM expression in 721B whole cell lysate.| Product Name | T3JAM Antibody (Q-24) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | recommended for detection of T3JAM of mouse and human origin by WB, IP and ELISA |
| Modification Notes | T3JAM (TRAF3 interacting protein 3), also known as TRAF3-interacting JNK-activating modulator or TRAF3IP3, is a 551 amino acid single-pass type IV membrane protein that acts as an adaptor molecule and stimulates cell growth by modulating the c-Jun N-terminal kinase (JNK) pathway in conjunction with TRAF3. Expressed in thymus, bone marrow and spleen, T3JAM binds the isoleucine zipper of TRAF3 with its coiled-coil domain. T3JAM has been found to associate specifically with TRAF3 but not with other TRAF family members. As a result of alternative splicing events, three T3JAM isoforms exist. The gene encoding T3JAM maps to human chromosome 1, which spans about 260 million base pairs and comprises nearly 8% of the human genome. Aberrations in chromosome 1 are found in a variety of cancers including head and neck cancer, malignant melanoma and multiple myeloma. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPELISA |
| WB:1:500~1:2000 IP:1:100~1:500 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | recommended for detection of T3JAM of mouse and human origin by WB IP and ELISA |
|---|---|
| Tissue Specificity | recommended for detection of T3JAM of mouse and human origin by WB, IP and ELISA |
| Entrez Gene | 80342 |
|---|
Application
Western blot analysis of T3JAM expression in 721B whole cell lysate.| Application Notes | WB:1:500~1:2000 IP:1:100~1:500 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
