Application
Western blot analysis of DGCR14 expression in non-transfected 293T: (A), human DGCR14 transfected 293T: (B) and K-562 (C) whole cell lysates.| Product Name | DGCR14 Antibody (N-12) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope mapping at the N-terminus of DGCR14 of human origin |
| Modification Notes | DGCR14 (DiGeorge syndrome critical region 14, ES2 protein) is a 476 amino acid nuclear protein that belongs to the DGCR14 family. DGCR14 is believed to play a part in the etiology of the velocardiofacial/DiGeorge syndrome (VCFS/DGS), a developmental disorder characterized by structural and functional palate anomalies, conotruncal cardiac malformations, immunodeficiency, hypocalcemia, and typical facial anomalies. Most cases result from a deletion of chromosome 22q11.2 (DiGeorge syndrome chromosome region, or DGCR). This protein localizes to the nucleus and co-purifies with C complex spliceosomes. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of DGCR14 of human origin by WB, IP, IF and ELISA non cross-reactive with DGCR2 and DGCR6: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope mapping at the N-terminus of DGCR14 of human origin |
|---|---|
| Tissue Specificity | epitope mapping at the N-terminus of DGCR14 of human origin |
| Entrez Gene | 8220 |
|---|
Application
Western blot analysis of DGCR14 expression in non-transfected 293T: (A), human DGCR14 transfected 293T: (B) and K-562 (C) whole cell lysates.| Application Notes | recommended for detection of DGCR14 of human origin by WB, IP, IF and ELISA non cross-reactive with DGCR2 and DGCR6: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
