| Product Name | ZNF198 Antibody (S-20) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope mapping near the C-terminus of ZNF198 of human origin |
| Modification Notes | Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. ZNF198 (zinc finger 198), also known as ZMYM2 (zinc finger, MYM-type 2), FIM, MYM, RAMP or SCLL, is a 1,377 amino acid protein that localizes to the nucleus and contains nine MYM-type zinc fingers. Thought to be a component of the BHC histone deacetylase complex, ZNF198 interacts with HDAC1 and HDAC2 and is thought to stabilize the BHC complex via its MYM-type zinc fingers. The gene encoding ZNF198 is subject to a translocation with Flg, an event that may be involved in the pathogenesis of stem cell leukemia lymphoma syndrome (SCLL), a lymphoblastic lymphoma often accompanied by pronounced peripheral eosinophilia and/or prominent eosinophilic infiltrates in the affected bone marrow. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIFELISA |
| recommended for detection of ZNF198 of mouse, rat and human origin by WB, IF and ELISA non cross-reactive with other ZNF family members also reactive with additional species, including canine and avian: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope mapping near the C-terminus of ZNF198 of human origin |
|---|---|
| Tissue Specificity | epitope mapping near the C-terminus of ZNF198 of human origin |
| Entrez Gene | 7750 |
|---|
| Application Notes | recommended for detection of ZNF198 of mouse, rat and human origin by WB, IF and ELISA non cross-reactive with other ZNF family members also reactive with additional species, including canine and avian: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
