| Product Name | SAPS2 Antibody (N-20) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope mapping at the N-terminus of SAPS2 of human origin |
| Modification Notes | SAPS2 (SAPS domain family, member 2), also known as PP6R2, KIAA0685 or SAP190, is a 966 amino acid protein that localizes to the cytoplasm and exists as multiple alternatively spliced isoforms. Expressed ubiquitously with strongest levels present in testis, heart, liver, brain, kidney and placenta, SAPS2 functions as a regulatory subunit of the PP6 (protein phosphatase 6) holoenzyme that may play a role in protein scaffolding and I˚B-ε degradation. The gene encoding SAPS2 maps to human chromosome 22, which houses over 500 genes and is the second smallest human chromosome. Mutations in several of the genes that map to chromosome 22 are involved in the development of Phelan-McDermid syndrome, Neurofibromatosis type 2, autism and schizophrenia. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of SAPS2 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine and canine: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope mapping at the N-terminus of SAPS2 of human origin |
|---|---|
| Tissue Specificity | epitope mapping at the N-terminus of SAPS2 of human origin |
| Entrez Gene | 9701 |
|---|
| Application Notes | recommended for detection of SAPS2 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine and canine: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
