| Product Name | MRAP Antibody (T-18) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope mapping within an extracellular domain of MRAP of human origin |
| Modification Notes | MRAP (melanocortin 2 receptor accessory protein), also known as B27, C21orf61 or FALP, is a 172 amino acid protein that localizes to both the cell membrane and the cytoplasm. Expressed in testis, ovary, lymph node, thyroid and fat tissue, MRAP is involved in intracellular trafficking pathways in adipocyte cells and is required for the proper processing and function of MC2-R. Defects in the gene encoding MRAP are the cause of glucocorticoid deficiency type 2 (GCCD2), an autosomal recessive disorder that is characterized by progressive primary adrenal insufficiency due to congenital insensitivity or resistance to adrenocorticotropin. MRAP is expressed as four alternatively spliced isoforms that are encoded by a gene which maps to human chromosome 21. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIFELISA |
| recommended for detection of MRAP of human origin by WB, IF and ELISA: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope mapping within an extracellular domain of MRAP of human origin |
|---|---|
| Tissue Specificity | epitope mapping within an extracellular domain of MRAP of human origin |
| Entrez Gene | 56246 |
|---|
| Application Notes | recommended for detection of MRAP of human origin by WB, IF and ELISA: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
