Application
Western blot analysis of STCH expression in HEK293 (A), U-937 (B), Caco-2 (C), A-431 (D), Hep G2 (E) and K-562 (F) whole cell lysates.| Product Name | STCH Antibody (N-16) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope mapping near the N-terminus of STCH of human origin |
| Modification Notes | The heat shock proteins (HSPs) comprise a group of highly conserved, abundantly expressed proteins with diverse functions, which include the assembly and sequestering of multiprotein complexes, transportation of nascent polypeptide chains across cellular membranes and regulation of protein folding. Heat shock proteins (also known as molecular chaperones) fall into six general families: HSP 90, HSP 70, HSP 60, the low molecular weight HSPs, the immunophilins and the HSP 105 family. STCH, also known as HSPA13 (heat shock 70 kDa protein, member 13) or microsomal stress 70 protein ATPase core, is a 471 amino acid protein belonging to the HSP 70 protein family. Localized to the Endoplasmic Reticulum, STCH has peptide-independent ATPase activity. Fundamentally expressed in all tissues, STCH has been found to interact with PLIC-1 and PLIC-2, proteins involved in the signaling connection between the membrane receptors for Thrombospondin and the cytoskeleton. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of STCH of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine, porcine and avian: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope mapping near the N-terminus of STCH of human origin |
|---|---|
| Tissue Specificity | epitope mapping near the N-terminus of STCH of human origin |
| Entrez Gene | 6782 |
|---|
Application
Western blot analysis of STCH expression in HEK293 (A), U-937 (B), Caco-2 (C), A-431 (D), Hep G2 (E) and K-562 (F) whole cell lysates.| Application Notes | recommended for detection of STCH of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine, porcine and avian: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
