epitope corresponding to amino acids 28-135 mapping near the N-terminus of ALCAM of human origin
Modification Notes
Activated leukocyte cell adhesion molecule (ALCAM), expressed on activated leukocytes T cells, B cells and monocytes, is a member of the immunoglobulin superfamily (IgSF) and identified as a CD6 ligand. CD6 is a type I membrane protein in the scavenger receptor cysteine rich protein superfamily that acts in T cell adhesion and costimulation. ALCAM mediates thymocyte-thymic epithelial cell adhesion via homophilic (ALCAM-ALCAM) and heterophilic (ALCAM-CD6) interactions involving a previously undescribed protein-protein interaction between a member of the scavenger receptor cysteine rich protein superfamily and the immunoglobulin superfamily.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WBIPIFELISA
recommended for detection ALCAM of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine and porcine:
Species Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Alternative Names
epitope corresponding to amino acids 28-135 mapping near the N-terminus of ALCAM of human origin
Tissue Specificity
epitope corresponding to amino acids 28-135 mapping near the N-terminus of ALCAM of human origin
Immunofluorescence staining of normal mouse heart frozen section showing membrane and cytoplasmic staining.
Application
Western blot analysis of ALCAM expression in Daudi whole cell lysate.
Application Notes
recommended for detection ALCAM of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine and porcine:
Additional Information
Form
Liquid
Storage Instructions
For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.