recommended for detection of BCNP1 of human origin by WB, IP, IF and IHC(P)
Modification Notes
BCNP1 (B-cell novel protein 1), also known as FAM129C (family with sequence similarity 129, member C) or Niban-like protein 2, is a 697 amino acid protein that belongs to the Niban family. Specifically expressed in B-lymphocytes, BCNP1 exists as five alternatively spliced isoforms. BCNP1 is highly expressed in B-cell malignancies, lymph node and spleen, with little to no expression in other tissues, including other hemopoietic tissues. The gene encoding the BCNP1 protein maps to human chromosome 19p13.11. Consisting of around 63 million bases with over 1,400 genes, chromosome 19 makes up over 2% of human genomic DNA. Chromosome 19 includes a diversity of interesting genes and is recognized for having the greatest gene density of the human chromosomes. It is the genetic home for a number of immunoglobulin superfamily members including the killer cell and leukocyte Ig-like receptors, a number of ICAMs, the CEACAM and PSG family, and Fcå receptors. Key genes for eye color and hair color also map to chromosome 19.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WBIPIFIHC
WB:1:500~1:2000 IP:1:100~1:500 IF:1:200~1:500 IHC:1:50~1:200 Notes:Optimal dilutions/concentrations should be determined by the researcher.
Species Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Alternative Names
recommended for detection of BCNP1 of human origin by WB IP IF and IHC(P)
Tissue Specificity
recommended for detection of BCNP1 of human origin by WB, IP, IF and IHC(P)