| Product Name | CLEC-2B Antibody (H-50) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 41-90 mapping within an internal region of CLEC-2B of human origin |
| Modification Notes | The C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily consists of a variety of proteins that share a common protein fold and have diverse functions, including cell-cell signaling, cell adhesion, glycoprotein turnover and immune responses. CLEC-2B (C-type lectin domain family 2 member B), also known as IFNRG1 (IFN-alpha2b-inducing-related protein 1) and AICL (Activation-induced C-type lectin), is a 149 amino acid membrane protein that contains one extracellular C-type lectin domain near its carboxyl-terminus. The CLEC-2B gene is located within the natural killer gene complex, which includes genes encoding for CD69, CLEC-2D, CD161 and CD94. Since downregulation of CLEC-2B reduces NK cell-mediated cytotoxicity towards target cells and it is expressed in lymphoid tissues, CLEC-2B is thought play a role in the immune system. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of CLEC-2B of human origin by WB, IP, IF and ELISA: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 41-90 mapping within an internal region of CLEC-2B of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 41-90 mapping within an internal region of CLEC-2B of human origin |
| Application Notes | recommended for detection of CLEC-2B of human origin by WB, IP, IF and ELISA: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
