Application
Western blot analysis of TAF6L expression in Jurkat whole cell lysate.| Product Name | TAF6L Antibody (E-21) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | raised against TAF6L of human origin |
| Modification Notes | In eukaryotic systems, the process of initiating transcription from protein-coding genes requires the presence of RNA polymerase II and a broad family of auxiliary transcription factors. TFIID is a general transcription factor that initiates preinitiation complex assembly through direct interaction with the TATA promoter element. Functioning as a multisubunit complex consisting of a small TATA-binding polypeptide and other TBP-associated factors (TAFs), TFIID mediates promoter responses to various transcriptional activators and repressors. TAF6L, also known as PAF65A, is a 622 amino acid nuclear protein that functions as part of the PCAF (p300/CBP-associated factor) histone acetylase complex. Working in conjunction with several other TAF proteins, TAF6L acetylates nucleosomal histones, a process that is required for proper transcription and differentiation. Upon DNA damage, TAF6L may be phosphorylated by ATR or ATM. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPELISA |
| recommended for detection of TAF6L of mouse, rat, human and canine origin by WB, IP and ELISA: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | raised against TAF6L of human origin |
|---|---|
| Tissue Specificity | raised against TAF6L of human origin |
| Entrez Gene | 10629 |
|---|
Application
Western blot analysis of TAF6L expression in Jurkat whole cell lysate.| Application Notes | recommended for detection of TAF6L of mouse, rat, human and canine origin by WB, IP and ELISA: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
