Application
Western blot analysis of AP-2ε expression in transfected 293T whole cell lysate.| Product Name | AP-2ε Antibody (T-25) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | raised against AP-2ε of human origin |
| Modification Notes | AP-2 transcription factor family members include AP-2å, AP-2∫, AP-2©, AP-2∂ and AP-2é, which specifically bind to DNA and regulate transcription of selected genes. AP-2 proteins contain a helix-span-helix motif at their C-terminus and a basic central region that, together, mediate DNA binding and dimerization. AP-2 family members have various roles in apoptosis, development, morphogenesis and cell-cycle control. AP-2é, also known as TFAP2E or AP2E, is a nuclear protein and is predominantly expressed in skin, HeLa cells, primary keratinocytes and immortalized keratinocytes. AP-2é binds to DNA as a dimer, associated either as a homodimer or as a heterodimer with other members of the AP-2 family. Due to its high level of expression in skin, AP-2é is believed to play an important role in skin biology. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPELISA |
| recommended for detection of AP-2ε of h and r origin by WB, IP and ELISA: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | raised against AP-2&epsilon of human origin |
|---|---|
| Tissue Specificity | raised against AP-2ε of human origin |
| Entrez Gene | 339488 |
|---|
Application
Western blot analysis of AP-2ε expression in transfected 293T whole cell lysate.| Application Notes | recommended for detection of AP-2ε of h and r origin by WB, IP and ELISA: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
