Application
Western blot analysis of CYP2B6 expression in A549 whole cell lysate.| Product Name | CYP2B6 Antibody (H-110) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 186-295 mapping within an internal region of CYP2B6 of human origin |
| Modification Notes | CYP2B6 (cytochrome P450 2B6) is a 491 amino acid protein encoded by the human gene CYP2B6. CYP genes are highly polymorphic and can affect individual drug response and adverse reactions to a great extent. The CYP2B6 gene product, along with a few other CYP gene products, are highly susceptible to variation due to several copy number variants (CNV), missense mutations, insertions and deletions, and gene expression mutations. There are 57 active CYP genes and 58 pseudogenes known in the human genome. In liver microsomes, CYP2B6 is involved in an NADPH-dependent electron transport pathway. It acts to oxidize a variety of structurally unrelated compounds, including steroids, fatty acids and xenobiotics. CYP2B6 is expressed in liver, lung and heart and can be induced by phenobarbital. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of CYP2B6 of human origin by WB, IP, IF and ELISA: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 186-295 mapping within an internal region of CYP2B6 of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 186-295 mapping within an internal region of CYP2B6 of human origin |
| Entrez Gene | 1555 |
|---|
Application
Western blot analysis of CYP2B6 expression in A549 whole cell lysate.| Application Notes | recommended for detection of CYP2B6 of human origin by WB, IP, IF and ELISA: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
