epitope corresponding to amino acids 313-350 mapping at the C-terminus of MafA of human origin
Modification Notes
Members of the bZIP containing Maf transcription factor family play important roles in cellular differentiation and regulation. MafA, originally identified in mammals as the pancreatic b-cell specific RIPE3b1 factor, is a transcriptional activator expressed specifically in insulin-producing cells, where it functions by binding to the critical insulin enhancer element RIPE3b. MafA is critical for generating and regulating glucose-reponsive insulin expression in b cells. The size of MafA in mammalian cell lines varies, due to posttranslational modification of the protein.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WBIPIFELISAGSChIP
recommended for detection of MafA of mouse, rat and human origin by WB, IP, IF and ELISA:
Species Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Alternative Names
epitope corresponding to amino acids 313-350 mapping at the C-terminus of MafA of human origin
Tissue Specificity
epitope corresponding to amino acids 313-350 mapping at the C-terminus of MafA of human origin