Application
Western blot analysis of Calpain 9 expression in HISM whole cell lysate.Application
Western blot analysis of Calpain 9 expression in TF-1 whole cell lysate.Application
Western blot analysis of Calpain 9 expression in non-transfected: (A) and human Calpain 9 transfected: (B) 293T whole cell lysates.| Product Name | Calpain 9 Antibody (H-210) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 481-690 mapping at the C-terminus of Calpain 9 of human origin |
| Modification Notes | Calpain 9 belongs to a family of 14 intracellular calcium activated cysteine proteases present in the fungi, plant and animal kingdoms. Several of these proteases have been implicated in cardiovascular diseases. On a high salt diet, Calpain 9 is downregulated by more than 50% in the heart. The differential regulation of Calpain 9 seen under such conditions may play a role in hypertensive target organ damage. The digestive tract-specific Calpain 9 is downregulated in gastric cancer cell lines, suggesting that it acts as a gastric cancer suppressor. Two known isoforms exist for Calpain 9 due to alternative splicing. The two isoforms vary in their amino acid sequences between amino acids 292 and 318. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of Calpain 9 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine and porcine: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 481-690 mapping at the C-terminus of Calpain 9 of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 481-690 mapping at the C-terminus of Calpain 9 of human origin |
| Entrez Gene | 10753 |
|---|
Application
Western blot analysis of Calpain 9 expression in HISM whole cell lysate.
Application
Western blot analysis of Calpain 9 expression in TF-1 whole cell lysate.
Application
Western blot analysis of Calpain 9 expression in non-transfected: (A) and human Calpain 9 transfected: (B) 293T whole cell lysates.| Application Notes | recommended for detection of Calpain 9 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine and porcine: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
