Application
Western blot analysis of human recombinant VEGF-B fusion protein.| Product Name | VEGF-B Antibody (H-70) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 1-70 mapping at the N-terminus of VEGF-B of human origin |
| Modification Notes | The onset of angiogenesis is believed to be an early event in tumorigenesis and may facilitate tumor progression and metastasis. Several growth factors with angiogenic activity have been described and include fibroblast growth factor (FGF), platelet derived growth factor (PDGF) and vascular endothelial growth factors (VEGFs). The VEGF protein family is comprised of VEGF, VEGF-B, VEGF-C and VEGF-D, all of which may exhibit angiogenic function in vivo. VEGF-B, which exists as two alternatively spliced isoforms known as VEGF-B167 and VEGF-B186, is abundantly expressed in heart and skeletal muscle and is frequently co-expressed with VEGF. VEGF-C binds to and specifically activates Flt-4 and Flk-1. The genes that encode human VEGF-B and VEGF-C have been localized to chromosomes 11q13 and 4q34, respectively. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of VEGF-B of mouse, rat and human origin by WB, IP, IF,IHC and ELISA also reactive with additional species, including bovine and porcine: WB:1:100~1:200 IHC:1:10~1:50 IF:1:20~1:100 IP:1:20~1:100 |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 1-70 mapping at the N-terminus of VEGF-B of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 1-70 mapping at the N-terminus of VEGF-B of human origin |
| Entrez Gene | 7423 |
|---|
Application
Western blot analysis of human recombinant VEGF-B fusion protein.| Application Notes | recommended for detection of VEGF-B of mouse, rat and human origin by WB, IP, IF,IHC and ELISA also reactive with additional species, including bovine and porcine: WB:1:100~1:200 IHC:1:10~1:50 IF:1:20~1:100 IP:1:20~1:100 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
