Application
Western blot analysis of human recombinant Tom1 fusion protein.Application
Western blot analysis of Tom1 expression in non-transfected: (A) and human Tom1 transfected: (B) 293T whole cell lysates.| Product Name | Tom1 Antibody (H-72) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 368-439 mapping near the C-terminus of Tom1 of human origin |
| Modification Notes | Tom1 (Target of Myb 1) is a 492 amino acid cytoplasmic protein that belongs to the Tom1 family. Widely expressed with highest expression in heart, liver, placenta and skeletal muscle, Tom1 is thought to be involved in intracellular trafficking and may be associated with the translocation of ubiquitinated proteins to early endosomes for degradation. Tom1 contains one GAT domain and one VHS domain through which it interacts and complexes with proteins such as Tollip and endofin (also known as SARA). These interactions recruit Tom1 to the endosome, allowing it to participate in the endosomal trafficking of ubiquitin-tagged proteins. Human Tom1 shares 76% similarity with its chicken counterpart and 89% similarity with its mouse counterpart, suggesting a conserved function between species. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| suitable control antibody: : sc-Tom1 (h): 293T Lysate: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 368-439 mapping near the C-terminus of Tom1 of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 368-439 mapping near the C-terminus of Tom1 of human origin |
| Entrez Gene | 10043 |
|---|
Application
Western blot analysis of human recombinant Tom1 fusion protein.
Application
Western blot analysis of Tom1 expression in non-transfected: (A) and human Tom1 transfected: (B) 293T whole cell lysates.| Application Notes | suitable control antibody: : sc-Tom1 (h): 293T Lysate: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
