| Product Name | C11orf48 Antibody (C-14) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope mapping near the C-terminus of C11orf48 of human origin |
| Modification Notes | C11orf48 (chromosome 11 open reading frame 48), also known as MGC2477, is a 289 amino acid protein existing as two alternatively spliced isoforms and encoded by a gene located on human chromsome 11q12.3. With approximately 135 million base pairs and 1,400 genes, chromosome 11 makes up around 4% of human genomic DNA and is considered a gene and disease association dense chromosome. The chromosome 11 encoded Atm gene is important for regulation of cell cycle arrest and apoptosis following double strand DNA breaks. Atm mutation leads to the disorder known as ataxia-telangiectasia. The blood disorders Sickle cell anemia and ∫ thalassemia are caused by HBB gene mutations. Wilms' tumors, WAGR syndrome and Denys-Drash syndrome are associated with mutations of the WT1 gene. Jervell and Lange-Nielsen syndrome, Jacobsen syndrome, Niemann-Pick disease, hereditary angioedema and Smith-Lemli-Opitz syndrome are also associated with defects in chromosome 11. The C11orf48 gene product has been provisionally designated C11orf48 pending further characterization. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIFELISA |
| recommended for detection of C11orf48 of human origin by WB, IF and ELISA non cross-reactive with other C11orf family members: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope mapping near the C-terminus of C11orf48 of human origin |
|---|---|
| Tissue Specificity | epitope mapping near the C-terminus of C11orf48 of human origin |
| Entrez Gene | 79081 |
|---|
| Application Notes | recommended for detection of C11orf48 of human origin by WB, IF and ELISA non cross-reactive with other C11orf family members: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
