Application
Western blot analysis of GPR149 expression in mouse brain (A) and mouse cerebellum (B) tissue extracts.| Product Name | GPR149 Antibody (L-16) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope mapping within a cytoplasmic domain of GPR149 of human origin |
| Modification Notes | G protein-coupled receptors (GPRs), also known as seven transmembrane receptors, heptahelical receptors or 7TM receptors, comprise a superfamily of proteins that play a role in many different stimulus-response pathways. G protein coupled receptors translate extracellular signals into intracellular signals (G protein activation) and they respond to a variety of signaling molecules, such as hormones and neurotransmitters. GPR149 (G protein-coupled receptor 149), also known as PGR10 or IEDA, is a 731 amino acid multi-pass membrane protein that functions as an orphan receptor and belongs to the G protein-coupled receptor family. The gene encoding GPR149 maps to human chromosome 3, which houses over 1,100 genes, including a chemokine receptor (CKR) gene cluster and a variety of human cancer-related gene loci. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of GPR149 of mouse, rat and human origin by WB, IP, IF and ELISA non cross-reactive with other GPR family members also reactive with additional species, including porcine: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope mapping within a cytoplasmic domain of GPR149 of human origin |
|---|---|
| Tissue Specificity | epitope mapping within a cytoplasmic domain of GPR149 of human origin |
| Entrez Gene | 344758 |
|---|
Application
Western blot analysis of GPR149 expression in mouse brain (A) and mouse cerebellum (B) tissue extracts.| Application Notes | recommended for detection of GPR149 of mouse, rat and human origin by WB, IP, IF and ELISA non cross-reactive with other GPR family members also reactive with additional species, including porcine: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
