epitope mapping within an internal region of ZFAND1 of human origin
Modification Notes
Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The majority of zinc-finger proteins contain a Krüppel-type DNA binding domain and a KRAB domain, which is thought to interact with KAP1, thereby recruiting histone modifying proteins. ZFAND1 (AN1-type zinc finger protein 1) is a 268 amino acid protein that contains 2 AN1-type zinc fingers, which are often found in proteins that contain a ubiquitin-like domain and therefore play a role in the ubiquitination pathway. AN1-type zinc fingers contains six conserved cysteines and two histidines and have a dimetal (zinc)-bound alpha/beta fold. There are two isoforms of ZFAND1 that are produced as a result of alternative splicing events.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WBIPIFELISA
recommended for detection of ZFAND1 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including canine and porcine:
Species Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Alternative Names
epitope mapping within an internal region of ZFAND1 of human origin
Tissue Specificity
epitope mapping within an internal region of ZFAND1 of human origin
Western blot analysis of ZFAND1 expression in non-transfected: (A) and mouse ZFAND1 transfected: (B) 293T whole cell lysates.
Application Notes
recommended for detection of ZFAND1 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including canine and porcine:
Additional Information
Form
Liquid
Storage Instructions
For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.