Application
Western blot analysis of C9orf98 expression in non-transfected 293T: (A), human C9orf98 transfected 293T: (B), A-431 (C) and HeLa (D) whole cell lysates.| Product Name | AK8 Antibody (G-12) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope mapping within an internal region of AK8 of human origin |
| Modification Notes | Chromosome 9 consists of about 145 million bases and 4% of the human genome and encodes nearly 900 genes. Considered to play a role in gender determination, deletion of the distal portion of 9p can lead to development of male to female sex reversal, the phenotype of a female with a male X,Y genotype. Hereditary hemorrhagic telangiectasia, which is characterized by harmful vascular defects, is associated with the chromosome 9 gene encoding endoglin protein, ENG. Familial dysautonomia is also associated with chromosome 9 though through the gene IKBKAP. Notably, chromosome 9 encompasses the largest interferon family gene cluster. Chromosome 9 is partnered with chromosome 22 in the translocation leading to the aberrant production of BCR-ABL fusion protein often found in leukemias. The C9orf98 gene maps to human chromosome 9q34.13. Consisting of 479 amino acids, C9orf98 exists as two alternatively spliced isoforms and belongs to the adenylate kinase family. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of AK8 isoforms 1 and 2 of mouse, rat and human origin by WB, IP, IF and ELISA non cross-reactive with other C9orf family members also reactive with additional species, including equine: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope mapping within an internal region of AK8 of human origin |
|---|---|
| Tissue Specificity | epitope mapping within an internal region of AK8 of human origin |
| Entrez Gene | 158067 |
|---|
Application
Western blot analysis of C9orf98 expression in non-transfected 293T: (A), human C9orf98 transfected 293T: (B), A-431 (C) and HeLa (D) whole cell lysates.| Application Notes | recommended for detection of AK8 isoforms 1 and 2 of mouse, rat and human origin by WB, IP, IF and ELISA non cross-reactive with other C9orf family members also reactive with additional species, including equine: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
