Application
Western blot analysis of RPTPα expression in non-transfected: (A) and human RPTPα transfected: (B) 293T whole cell lysates.Application
Western blot analysis of RPTPα expression in non-transfected: (A) and human RPTPα transfected: (B) 293T whole cell lysates.| Product Name | RPTPα Antibody (H-200) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 21-220 of RPTPα of human origin |
| Modification Notes | Receptor protein-tyrosine phosphatase a (RPTPa) dephosphorylates and activates Src family tyrosine kinases and influences the regulation of integrin signaling, cell adhesion and growth factor responsiveness. RPTPa contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and constitutively forms dimers in the membrane. The human RPTPa sequence encodes a 793 amino acid protein. Mouse RPTPa precipitated from NIH/3T3 cells is constitutively phosphorylated at Ser 180/Ser 204. RPTPa also serves as a receptor for Helicobacter pylori vacuolating cytotoxin, VacA. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of RPTPα of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including bovine and equine: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 21-220 of RPTP&alpha of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 21-220 of RPTPα of human origin |
| Entrez Gene | 5786 |
|---|
Application
Western blot analysis of RPTPα expression in non-transfected: (A) and human RPTPα transfected: (B) 293T whole cell lysates.
Application
Western blot analysis of RPTPα expression in non-transfected: (A) and human RPTPα transfected: (B) 293T whole cell lysates.| Application Notes | recommended for detection of RPTPα of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including bovine and equine: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
