| Product Name | β-defensin 3 Antibody (FL-67) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 1-67 representing full length β-defensin 3 of human origin |
| Conjugation | Agarose |
| Modification | Acetylated |
| Modification Notes | ß-defensins (also designated BD, and hBD in human) are small cationic peptides with broad-spectrum antimicrobial activity. Produced in mucosal epithelia and neutrophils of several species, ∫-defensins are developmentally regulated. Human ß-defensin 2 is locally regulated by inflammation and is the first member of the ß-defensin family that is locally inducible by inflammation. The murine homolog of human ß-defensin 2, which is called ∫-defensin 3, is present in the respiratory system and in low levels in the epithelial cells of the intestine and lung. The unique murine ß-defensin 2 (Defb2) is not expressed in airways of untreated mice, but is upregulated in the airways by lipopolysaccharide and may contribute to host defense at the mucosal surface of the airways. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | ELISAIFIPWB |
| WB:1:100~1:500 IP:1:20~1:100 IF:1:20~1:100 |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 1-67 representing full length β-defensin 3 of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 1-67 representing full length β-defensin 3 of human origin |
| Entrez Gene | 55894 |
|---|
| Application Notes | WB:1:100~1:500 IP:1:20~1:100 IF:1:20~1:100 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
