| Product Name | TMEM200A Antibody (N-17) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope mapping within an N-terminal cytoplasmic domain of TMEM200A of human origin |
| Modification Notes | TMEM200A (transmembrane protein 200A), also known as TTMA or TTMC, is a 491 amino acid multi-pass membrane protein that is expressed in cerebellum and belongs to the TMEM200 family. The gene encoding TMEM200A maps to human chromosome 6q23.1 and mouse chromosome 10 A4. Making up nearly 6% of the human genome, chromosome 6 contains around 1,200 genes within 170 million base pairs of sequence. Deletion of a portion of the q arm of chromosome 6 is associated with early onset intestinal cancer suggesting the presence of a cancer susceptibility locus. Porphyria cutanea tarda is associated with chromosome 6 through the HFE gene which, when mutated, predisposes an individual to developing this porphyria. Stickler syndrome, Parkinson’s disease, 21-hydroxylase deficiency and maple syrup urine disease are also associated with genes on chromosome 6. A bipolar disorder susceptibility locus has been identified on the q arm of chromosome 6. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIFELISA |
| recommended for detection of TMEM200A of mouse, rat and human origin by WB, IF and ELISA non cross-reactive with other KIAA family members also reactive with additional species, including equine and porcine: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope mapping within an N-terminal cytoplasmic domain of TMEM200A of human origin |
|---|---|
| Tissue Specificity | epitope mapping within an N-terminal cytoplasmic domain of TMEM200A of human origin |
| Entrez Gene | 114801 |
|---|
| Application Notes | recommended for detection of TMEM200A of mouse, rat and human origin by WB, IF and ELISA non cross-reactive with other KIAA family members also reactive with additional species, including equine and porcine: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
