Application
Western blot analysis of DTYMK expression in LNCaP (A), MDA-MB-231 (B), ES-2 (C) and Hep G2 (D) whole cell lysates.Application
Western blot analysis of DTYMK expression in HeLa (A), K-562 (B) and MOLT-4 (C) whole cell lysates.| Product Name | DTYMK Antibody (FL-212) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 1-212 representing full length DTYMK of human origin |
| Modification Notes | DTYMK (deoxythymidylate kinase (thymidylate kinase)), also known as CDC8, TMPK, TYMK or dTMP kinase, is a 212 amino acid protein that belongs to the thymidylate kinase family and is involved in pyrimidine metabolism. Specifically, DTYMK catalyzes the ATP-dependent conversion of dTMP (deoxythymidine monophosphate) to dTDP (deoxythymidine diphosphate), which then functions as one of the four nucleotides in DNA. Via its role in the catalytic creation of dTDP, DTYMK plays an important role in the pathway of DNA synthesis and is thought to be involved in cell cycle progression and cell growth. DTYMK expression levels peak during the S phase (synthesis phase) of the cell cycle, further supporting the role of DTYMK in DNA synthesis. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of DTYMK of mouse, rat and human origin by WB, IP, IF and ELISA: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 1-212 representing full length DTYMK of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 1-212 representing full length DTYMK of human origin |
Application
Western blot analysis of DTYMK expression in LNCaP (A), MDA-MB-231 (B), ES-2 (C) and Hep G2 (D) whole cell lysates.
Application
Western blot analysis of DTYMK expression in HeLa (A), K-562 (B) and MOLT-4 (C) whole cell lysates.| Application Notes | recommended for detection of DTYMK of mouse, rat and human origin by WB, IP, IF and ELISA: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
