epitope corresponding to amino acids 1-100 mapping at the N-terminus of cholecystokinin precursor of human origin
Modification Notes
CCK (cholecystokinin) is a 115 amino acid secreted protein belonging to the gastrin/cholecystokinin family. CCK has been shown to stimulate the growth of pancreatic cancer. As a peptide hormone, CCK induces gallbladder contraction and the release of pancreatic enzymes in the gut. Binding of CCK to CCK-A receptors stimulates amylase release from the pancreas, while binding to CCK-B receptors stimulates gastric acid secretion. The function of CCK in the brain is not clear. The CCK precursor is cleaved by proteases to produce a number of active cholecystokinins including CCK58, CCK58 desnonopeptide, CCK39, CCK33, CCK25, CCK18, CCK12, CCK8, CCK7 and CCK5. The gene encoding CCK maps to human chromosome 3p22.1 and mouse chromosome 9 F4.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WBIPIFELISA
recommended for detection of CCK precursor and all active peptides of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including canine:
Species Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Alternative Names
epitope corresponding to amino acids 1-100 mapping at the N-terminus of cholecystokinin precursor of human origin
Tissue Specificity
epitope corresponding to amino acids 1-100 mapping at the N-terminus of cholecystokinin precursor of human origin
Western blot analysis of human recombinant CCK fusion protein.
Application Notes
recommended for detection of CCK precursor and all active peptides of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including canine:
Additional Information
Form
Liquid
Storage Instructions
For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.